Nightclub & Private Event Space in San Francisco’s Mission District

Full-service ultra-lounge and live entertainment

Bruno’s is a two-floor nightclub, cocktail lounge, and private event space at 20th & Mission in San Francisco. Every Friday and Saturday, DJs take over both floors: house and dance music upstairs, open format and crowd favorites downstairs. The rest of the week, the whole venue is yours for birthdays, corporate parties, and full buyouts.

Bruno’s nightclub sign lit up at night on Mission Street in San Francisco

Private Events & Venue Buyouts

Planning a holiday party, milestone birthday, or company event? Book a section, a full floor, or the entire venue. Bruno’s holds up to [165] guests, with a professional sound system, DJ booth, full bar, and bottle service, plus an event coordinator who handles the details.

Plan your event
People waiting in line outside Bruno's restaurant, which has a large black sign with yellow letters and a red rope barrier.

About Us

A beloved neighborhood institution reborn, Bruno's blends its storied legacy with a renewed commitment to local talent, community partnership, and Mission Street revitalization.

LEARN MORE ABOUT OUR STORY
A wooden wall decorated with various artwork, including a famous sketch of the Vitruvian Man, a surreal face, and mechanical gears, with a brown leather bench at the bottom.
DJ mixing music on a professional controller in front of colorful LED lights

Live Music & DJs

Friday and Saturday, 9pm–2am. House, EDM, and dance music upstairs; hip-hop, pop, and open format downstairs. Local and touring DJs every weekend. Check the lineup and follow along on Instagram.

SEE THIS WEEKEND’S LINEUP

Visit Us

2389 Mission St, San Francisco, CA 94110

Friday & Saturday: 9pm-2am

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